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Compression tests of a living cell: a contact detection problem

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F14%3A43897522" target="_blank" >RIV/60461373:22330/14:43897522 - isvavai.cz</a>

  • Result on the web

    <a href="http://www.tandfonline.com/doi/abs/10.1080/10255842.2014.931093?journalCode=gcmb20#.VLaWhytfZ8F" target="_blank" >http://www.tandfonline.com/doi/abs/10.1080/10255842.2014.931093?journalCode=gcmb20#.VLaWhytfZ8F</a>

  • DOI - Digital Object Identifier

    <a href="http://dx.doi.org/10.1080/10255842.2014.931093" target="_blank" >10.1080/10255842.2014.931093</a>

Alternative languages

  • Result language

    angličtina

  • Original language name

    Compression tests of a living cell: a contact detection problem

  • Original language description

    Alterations in the mechanical properties of cells are associated with cellular diversification and diseases. Assessment of mechanical properties of living cells was mostly associated with Atomic Force Microscopy technique. However, the contact conditionsof AFM tip with cell's membrane are very complex (Vichare et al. 2012). Advantageously, very well defined geometry of flat end probe used for nanoindentation can simplify the contact problem into compression of an inflated spherical membrane by two rigid parallel planes (Nadler 2010 and Arfsten et al. 2008). From our previous experiments we used COS-1 cells [ATCC, USA] because of their long viability and good adhesion properties. This cell line [ATCC code: CRL-1650] was derived from African green monkey kidney; the cells grow attached to the base (adherent) and have morphology of fibroblasts. The aims of present study are as follows: (1) Determination of the contact between flat punch tip and single cell and (2) to identify membrane bu

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    JD - Use of computers, robotics and its application

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/LH12011" target="_blank" >LH12011: Structure of retroviral particle and intracellular transport of its components.</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Others

  • Publication year

    2014

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Computer Methods in Biomechanics and Biomedical Engineering

  • ISSN

    1025-5842

  • e-ISSN

  • Volume of the periodical

    17

  • Issue of the periodical within the volume

    30.7.2014

  • Country of publishing house

    GB - UNITED KINGDOM

  • Number of pages

    2

  • Pages from-to

    40-41

  • UT code for WoS article

    000340376700021

  • EID of the result in the Scopus database