Compression tests of a living cell: a contact detection problem
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F68407700%3A21220%2F14%3A00217609" target="_blank" >RIV/68407700:21220/14:00217609 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1080/10255842.2014.931093" target="_blank" >http://dx.doi.org/10.1080/10255842.2014.931093</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1080/10255842.2014.931093" target="_blank" >10.1080/10255842.2014.931093</a>
Alternative languages
Result language
angličtina
Original language name
Compression tests of a living cell: a contact detection problem
Original language description
Alterations in the mechanical properties of cells are associated with cellular diversification and diseases. Assessment of mechanical properties of living cells was mostly associated with Atomic Force Microscopy technique. However, the contact conditions of AFM tip with cell’s membrane are very complex. Advantageously, very well defined geometry of flat end probe used for nanoindentation can simplify the contact problem into compression of an inflated spherical membrane by two rigid parallel planes. From our previous experiments we used COS-1 cells [ATCC, USA] because of their long viability and good adhesion properties. This cell line [ATCC code: CRL-1650] was derived from African green monkey kidney; the cells grow attached to the base (adherent) and have morphology of fibroblasts. The aims of present study are as follows: (1) Determination of the contact between flat punch tip and single cell and (2) to identify membrane bursting critical load.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
BO - Biophysics
OECD FORD branch
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Result continuities
Project
<a href="/en/project/TA01010185" target="_blank" >TA01010185: New materials and coatings for joint replacement bionical design</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Computer Methods in Biomechanics and Biomedical Engineering
ISBN
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ISSN
1025-5842
e-ISSN
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Number of pages
2
Pages from-to
40-41
Publisher name
Taylor & Francis
Place of publication
London
Event location
Valenciennes
Event date
Aug 27, 2014
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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