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Ti-alloy with nanotubular surface modification for orthopaedic applications

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F15%3A43901139" target="_blank" >RIV/60461373:22330/15:43901139 - isvavai.cz</a>

  • Alternative codes found

    RIV/60461373:22310/15:43901139

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Ti-alloy with nanotubular surface modification for orthopaedic applications

  • Original language description

    Titanium and its alloys have been widely used for permanent orthopaedic implants; however, they are considered as bioinert, which means that fibrous layer is often formed on the implant-bone interface. For better integration of the implant that could accelerate healing and prolong lifespan of the implant, material surfaces can be modified in various ways. It has been shown that nanotopography influences cell adhesion and differentiation1. Anodic oxidation in appropriate electrolytes2 is a method which can be used for scale-up nanopatterning of metallic materials. Specific parameters of the nanotubes and their influence on the cell growth have been extensively studied recently. Interestingly, various authors obtained contradictory results when performing in vitro tests with TiO2 nanotubes (diameter 15 - 100 nm) using mesenchymal stem cells (MSCs) 3, 4. Our aim was to perform in vitro tests with nanotubular surfaces on commercial titanium alloy and to study the influence of the nanostruc

  • Czech name

  • Czech description

Classification

  • Type

    O - Miscellaneous

  • CEP classification

    EB - Genetics and molecular biology

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/TE01020390" target="_blank" >TE01020390: Centre of the development of advanced metallic biomaterials for medical implants</a><br>

  • Continuities

    P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach

Others

  • Publication year

    2015

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů