Ti-alloy with nanotubular surface modification for orthopaedic applications
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F15%3A43901139" target="_blank" >RIV/60461373:22330/15:43901139 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22310/15:43901139
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Ti-alloy with nanotubular surface modification for orthopaedic applications
Original language description
Titanium and its alloys have been widely used for permanent orthopaedic implants; however, they are considered as bioinert, which means that fibrous layer is often formed on the implant-bone interface. For better integration of the implant that could accelerate healing and prolong lifespan of the implant, material surfaces can be modified in various ways. It has been shown that nanotopography influences cell adhesion and differentiation1. Anodic oxidation in appropriate electrolytes2 is a method which can be used for scale-up nanopatterning of metallic materials. Specific parameters of the nanotubes and their influence on the cell growth have been extensively studied recently. Interestingly, various authors obtained contradictory results when performing in vitro tests with TiO2 nanotubes (diameter 15 - 100 nm) using mesenchymal stem cells (MSCs) 3, 4. Our aim was to perform in vitro tests with nanotubular surfaces on commercial titanium alloy and to study the influence of the nanostruc
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
EB - Genetics and molecular biology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/TE01020390" target="_blank" >TE01020390: Centre of the development of advanced metallic biomaterials for medical implants</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>S - Specificky vyzkum na vysokych skolach
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů