Determination of major phytocannabinoids employing ultra-high performance liquid chromatography coupled to high resolution tandem mass spectrometry technique
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F15%3A43901502" target="_blank" >RIV/60461373:22330/15:43901502 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Determination of major phytocannabinoids employing ultra-high performance liquid chromatography coupled to high resolution tandem mass spectrometry technique
Original language description
In any case, effective analytical control of cannabinoids levels in respective plants and products is of a high concern. Currently, liquid chromatography separation coupled to mass spectrometric detection is a preferred technique used for cannabinoids analysis since it provides sufficiently low limits of quantification (LOQ) in a variety of matrices. One of the analytical challenges encountered in phytocannabinoids analysis is a very wide range (even several orders of magnitude) of concentrations at which they occur in analyzed samples. This makes quantification process rather difficult, specifically when HR mass analyzers with a relatively narrow dynamic range (TOF, Orbitrap) are employed for detection. Within this study concerned simultaneous analysis of 7 phytocannabinoids, we focused on overcoming this problem by various settings of Q-Orbitrap analyzer combining different MS experiments in order to ensure sufficient sensitivity for low-abundant analytes and prevent from detector sa
Czech name
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Czech description
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Classification
Type
O - Miscellaneous
CEP classification
GM - Food industry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/TA04010331" target="_blank" >TA04010331: Characterization and selection of C. sativa for food and non-food use by means of biotechnological processes and high-performance methods.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů