Using nutritional and oxidative stress to increase content of health-beneficial fatty acids in oleaginous and non-oleaginous yeasts

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F16%3A43901627" target="_blank" >RIV/60461373:22330/16:43901627 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1515/chempap-2016-0060" target="_blank" >http://dx.doi.org/10.1515/chempap-2016-0060</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1515/chempap-2016-0060" target="_blank" >10.1515/chempap-2016-0060</a>

Result language

angličtina

Original language name

Using nutritional and oxidative stress to increase content of health-beneficial fatty acids in oleaginous and non-oleaginous yeasts

Original language description

Yeast responses to stress conditions include an increase in lipid content and concomitant changes in content of saturated and unsaturated fatty acids. Some fatty acids are among the dietetically important fatty acids and new possibilities are sought for their biotechnological production in addition to those already exploited from marine organisms, nuts and other sources. The possibility of the production of palmitoleic and linoleic acids resulting from new approaches to traditional biotechnologically useful yeast species (Kluyveromyces polysporus, Saccharomyces cerevisiae, Torulospora delbrueckii) and species capable of high accumulation of lipids (Rhodotorula glutinis, Trichosporon cutaneum, Candida sp., Yarrowia lipolytica) was explored. The most promising was the combination of two stress factors: limitation of N-sources (C/N mass ratio of 70 : 1) and oxidative stress induced by zero-valent iron nanoparticles. These conditions were conducive to the production of palmitoleic acid commonly used in cosmetics and medicine and omega-6-linoleic acid, a precursor of thromboxanes, prostaglandins and leucotrienes. The yield of these two fatty acids in T. cutaneum was more than 500 mg g(-1) (dry mass) and in Candida sp. more than 600 mg g(-1) (dry mass).

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

EI - Biotechnology and bionics

OECD FORD branch

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Project

<a href="/en/project/GA14-00227S" target="_blank" >GA14-00227S: Microorganisms as a source of essential fatty acids with focus on extremophile strains</a><br>

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chemical Papers

ISSN

0366-6352

e-ISSN

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Volume of the periodical

70

Issue of the periodical within the volume

10

Country of publishing house

SK - SLOVAKIA

Number of pages

9

Pages from-to

1351-1359

UT code for WoS article

000379758000005

EID of the result in the Scopus database

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