MOP and EE Protecting Groups in Synthesis of alpha- or beta-Naphthyl-C-Glycosides from Glycals

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F18%3A43915798" target="_blank" >RIV/60461373:22330/18:43915798 - isvavai.cz</a>
Alternative codes found
RIV/61388963:_____/18:00492083
Result on the web
<a href="http://dx.doi.org/10.1021/acsomega.8b00901" target="_blank" >http://dx.doi.org/10.1021/acsomega.8b00901</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1021/acsomega.8b00901" target="_blank" >10.1021/acsomega.8b00901</a>

Result language
angličtina
Original language name
MOP and EE Protecting Groups in Synthesis of alpha- or beta-Naphthyl-C-Glycosides from Glycals
Original language description
The development of effective protection strategies is essential in the synthesis of complex carbohydrates and glycomimetics. This article describes a versatile four-stage protocol for the synthesis of alpha- or beta-aryl-C-glycosides from unprotected D-glycals using two acetal protecting groups, ethoxyethyl and methoxypropyl, which are stable under harsh basic conditions and convenient for the C-1 metalation of glycals. Their stability was investigated in subsequent cross-coupling reactions with 1-iodonaphthalene followed by oxidative/reductive transformations to naphthyl-C-glycosides.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10401 - Organic chemistry

Project
<a href="/en/project/GA15-17572S" target="_blank" >GA15-17572S: Calix[4]arene/C-oligosaccharide glycoclusters design for improved selectivity of interactions with lectins</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Similar results(10)