Effect of non-thermal plasma on AHL-dependent QS systems and biofilm formation in Pseudomonas aeruginosa: Difference between non-hospital and clinical isolates
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F19%3A43918477" target="_blank" >RIV/60461373:22330/19:43918477 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/19:10400046
Result on the web
<a href="https://www.researchgate.net/publication/333302995_Effect_of_non-thermal_plasma_on_AHL-dependent_QS_systems_and_biofilm_formation_in_Pseudomonas_aeruginosa_Difference_between_non-hospital_and_clinical_isolates" target="_blank" >https://www.researchgate.net/publication/333302995_Effect_of_non-thermal_plasma_on_AHL-dependent_QS_systems_and_biofilm_formation_in_Pseudomonas_aeruginosa_Difference_between_non-hospital_and_clinical_isolates</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1063/1.5090451" target="_blank" >10.1063/1.5090451</a>
Alternative languages
Result language
angličtina
Original language name
Effect of non-thermal plasma on AHL-dependent QS systems and biofilm formation in Pseudomonas aeruginosa: Difference between non-hospital and clinical isolates
Original language description
Non-thermal plasma (NTP), generated by DC cometary discharge with a metallic grid at atmospheric pressure, was used to eradicate biofilm of Pseudomonas aeruginosa from titanium alloy Ti-6Al-4V carriers. The NTP exposure may reduce the ability of signal molecules to cause quorum sensing (QS) response in P. aeruginosa and as a result, affect the production of virulence factors including biofilm formation. Two groups of P. aeruginosa were compared, namely strains isolated from the environment (non-hospital) and clinical isolates from hospital environment. For the non-hospital strains, the inhibition of QS systems, mediated mainly by N-acyl-homoserine lactone (AHL) signals, and decrease of total biofilm biomass were observed after the NTP treatment. After 60 minutes of exposure, almost complete eradication of biofilm (54 - 98%) was achieved. Compared to that, the NTP effect on the AHL levels was more pronounced in clinical isolates of P. aeruginosa, but eradication of the biofilm was not achieved. We conclude that NTP affected the AHL-dependent QS systems (las and rhl), which does not necessarily have to result in the regulation of virulence in clinical isolates. (C) 2019 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10606 - Microbiology
Result continuities
Project
<a href="/en/project/GA17-15936S" target="_blank" >GA17-15936S: Interaction of nanoparticles modified by natural compounds with biofilms of pathogenic microorganisms</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
AIP Advances
ISSN
2158-3226
e-ISSN
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Volume of the periodical
9
Issue of the periodical within the volume
5
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
1-7
UT code for WoS article
000477701000050
EID of the result in the Scopus database
2-s2.0-85066151036