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Design of Mechanically Stirred Bioreactors and Exploitation of Control Software for Aerobic Cultivation of Microbial Cells

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F19%3A43918662" target="_blank" >RIV/60461373:22330/19:43918662 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Design of Mechanically Stirred Bioreactors and Exploitation of Control Software for Aerobic Cultivation of Microbial Cells

  • Original language description

    Control functions of the INFORS HT bioreactor Labfors 5 are described and discussed concerning their application for aerobic cultivation of dense cultures of microbial cells. A practical example was demonstrated cultivation of Pichia pastoris, facultative methylotrophic yeast producing under specific conditions recombinant proteins. A strategy of feeding the repressive and inducing substrates was tested aiming at the optimal process parameters. A similar example of computer-controlled cultivation is that of the yeast culture of Saccharomyces cerevisiae. The cultivation is performed in a fed-batch system and under special conditions can lead to an increased content of intracellular sterol - ergosterol (provitamin D2).

  • Czech name

  • Czech description

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

  • OECD FORD branch

    20902 - Bioprocessing technologies (industrial processes relying on biological agents to drive the process) biocatalysis, fermentation

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2019

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    Measurement and Control of Chemical, Food and Biotechnological Processes, Volume II: Process Control

  • ISBN

    978-1-908235-10-7

  • Number of pages of the result

    11

  • Pages from-to

    282-292

  • Number of pages of the book

    656

  • Publisher name

    STS Science Centre Ltd.

  • Place of publication

    London

  • UT code for WoS chapter