Determining the Effect of Polycyclic Aromatic Hydrocarbons Exposure on Cognitive Development in 5 Years Old Children: A Case Study in the Czech Republic
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F21%3A43922666" target="_blank" >RIV/60461373:22330/21:43922666 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Determining the Effect of Polycyclic Aromatic Hydrocarbons Exposure on Cognitive Development in 5 Years Old Children: A Case Study in the Czech Republic
Original language description
Objectives: To analyze the impact of polycyclic aromatic hydrocarbons (PAHs) in ambient air at the time of delivery and 5 years of age on cognitive development in 5 years old children. Materials and Methods: Two cohorts of children born in the year 2013 and 2014 from Karvina (Northern Moravia, N=70) and Ceske Budejovice (Southern Bohemia, N=99) were studied at the age of 5 years for their cognitive development related to the exposure to PAHs, determined in the ambient air as the concentration of benzo[a]pyrene (B[a]P) and OH-PAHs metabolites in urine of the newborns at the time of delivery. As psychological tests the Bender Visual Motor Gestalt Test (BG test) and the Raven Colored Progressive Matrices (RCPM test) were used. Results: Concentrations of B[a]P in the 3rd trimester of mother´s pregnancies were in Karvina 6.1±4.53 ng/m3, in Ceske Budejovice 1.19±1.28 ng/m3 (p<0.001). Neither the outcome of RCPM test nor BG test differ between children in Karvina vs. Ceske Budejovice, or boys vs. girls. Cognitive development in 5 years old children was affected by the higher exposure to PM2.5 during the third trimester in girls in Karvina. Conclusions: The rejection rate of part of mothers in our cohorts represents a considerable limitation in our research. We did not observe any significant effect of prenatal PAHs exposure on psychological cognitive tests in 5 years old children.
Czech name
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Czech description
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Classification
Type
C - Chapter in a specialist book
CEP classification
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OECD FORD branch
30304 - Public and environmental health
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Book/collection name
Recent Developments in Medicine and Medical Research
ISBN
978-93-5547-144-4
Number of pages of the result
17
Pages from-to
62-78
Number of pages of the book
191
Publisher name
B P International
Place of publication
Hooghly
UT code for WoS chapter
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