Are fish oil-based dietary supplements a significant source of exposure to chlorinated paraffins?

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22330%2F22%3A43925099" target="_blank" >RIV/60461373:22330/22:43925099 - isvavai.cz</a>

Result on the web

<a href="https://doi.org/10.1016/j.scitotenv.2022.155137" target="_blank" >https://doi.org/10.1016/j.scitotenv.2022.155137</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.scitotenv.2022.155137" target="_blank" >10.1016/j.scitotenv.2022.155137</a>

Result language

angličtina

Original language name

Are fish oil-based dietary supplements a significant source of exposure to chlorinated paraffins?

Original language description

Chlorinated paraffins (CPs) are an emerging group of environmental pollutants associated with adverse effects on human health (such as endocrine disruption and possible carcinogenicity). CPs are classified into several groups: short- (SCCPs), medium- (MCCPs) and long-chain chlorinated paraffins (LCCPs). In this study, CPs were determined in fish oil-based omega-3 dietary supplements (DS) representing widely consumed products that might be contaminated with various lipophilic contaminants including CPs. The CPs were isolated from DS (n = 85) by solid phase extraction. The SCCPs and MCCPs were determined by gas chromatography coupled with high-resolution mass spectrometry operated in a negative chemical ionisation mode. The LCCPs (up to C21) were screened using supercritical fluid chromatography coupled with high-resolution mass spectrometry with electrospray ionisation operated in negative mode. The CP concentrations varied from &lt;0.01 to 56.48 μg/g fat for SCCPs (median 0.12 μg/g fat; limit of quantification, LOQ, for SCCPs was exceeded in 51 out of 85 samples) and from &lt;0.03–89.08 μg/g fat for MCCPs (median 0.26 μg/g fat; LOQ for MCCPs was exceeded in 66 out of 85 samples), respectively. The LCCPs were not quantified in this study, nevertheless their limit of detection (0.5 μg/g fat) was exceeded in 7 out of 85 samples. Due to high levels of CPs, DS might pose as a significant source of CPs exposure to some population groups. © 2022 Elsevier B.V.

Czech name

—

Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

30308 - Nutrition, Dietetics

Project

<a href="/en/project/GA21-19437S" target="_blank" >GA21-19437S: Impact of emerging chlorinated contaminants on adipogeneses</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year

2022

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Science of the Total Environment

ISSN

0048-9697

e-ISSN

1879-1026

Volume of the periodical

833

Issue of the periodical within the volume

AUG 10 2022

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

nestrankovano

UT code for WoS article

000808120000011

EID of the result in the Scopus database

2-s2.0-85128576360