In vitro interaction of macrocyclic photosensitizers with intact mitochondria: a spectroscopic study
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F03%3A00007579" target="_blank" >RIV/60461373:22340/03:00007579 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22330/03:00007579
Result on the web
—
DOI - Digital Object Identifier
—
Alternative languages
Result language
angličtina
Original language name
In vitro interaction of macrocyclic photosensitizers with intact mitochondria: a spectroscopic study
Original language description
Six water-soluble macrocyclic photosensitizers, the members of two groups of expanded porphyrins (metallotexaphyrins and free-base sapphyrins) containing hydrophilic substituents and meso-tetra(4-sulfonatophenyl)-porphyrin, were tested by UV-Vis absorption and resonance Raman spectroscopy in the in vitro nibding experiments with intact mitochondria isolated form swine liver. Studied macrocycles showed markedly differenrt affinity to mitochondria. The highest uptake was observed for sapphyrin-sugar conjugate and metal-lotexaphirins. Sapphirin-polyamine conjugates exhibit something less affinity to mitochondria, while the porphyrin of anionic character showed very low mitochondrial uptake. Obtained spectroscopic results confirm that the binding process altered the self-aggregatio degree fo expanded porphyrins.
Czech name
—
Czech description
—
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CB - Analytical chemistry, separation
OECD FORD branch
—
Result continuities
Project
—
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2003
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biochimica and Biophysica Acta (BBA) - general subjects
ISSN
0006-3002
e-ISSN
—
Volume of the periodical
1620
Issue of the periodical within the volume
1
Country of publishing house
NL - THE KINGDOM OF THE NETHERLANDS
Number of pages
12
Pages from-to
85-96
UT code for WoS article
—
EID of the result in the Scopus database
—