Three-phase slug flow in microchips can provide beneficial reaction conditions for enzyme liquid-liquid reactions

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F13%3A43895780" target="_blank" >RIV/60461373:22340/13:43895780 - isvavai.cz</a>

Alternative codes found

RIV/49777513:23640/13:43919660

Result on the web

<a href="http://scitation.aip.org/content/aip/journal/bmf/7/5/10.1063/1.4821168" target="_blank" >http://scitation.aip.org/content/aip/journal/bmf/7/5/10.1063/1.4821168</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1063/1.4821168" target="_blank" >10.1063/1.4821168</a>

Result language

angličtina

Original language name

Three-phase slug flow in microchips can provide beneficial reaction conditions for enzyme liquid-liquid reactions

Original language description

Here, we introduce a solution to low stability of a two-phase slug flow with a chemical reaction occurring at the phase interface in a microfluidic reactor where substantial merging of individual reacting slugs results in the loss of uniformity of the flow. We create a three-phase slug flow by introducing a third fluid phase into the originally two-phase liquid-liquid slug flow, which generates small two-phase liquid slugs separated by gas phase. Introduction of the third phase into our system efficiently prevents merging of slugs and provides beneficial reaction conditions, such as uniform flow pattern along the whole reaction capillary, interfacial area with good reproducibility, and intensive water-oil interface renewal. We tested the three-phase flow on an enzyme hydrolysis of soybean oil and compared the reaction conversion with those from unstable two-phase slug flows. We experimentally confirmed that the three-phase slug flow arrangement provides conversions and pressure drops c

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CI - Industrial chemistry and chemical engineering

OECD FORD branch

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Project

<a href="/en/project/ED2.1.00%2F03.0088" target="_blank" >ED2.1.00/03.0088: Centre of the New Technologies and Materials</a><br>

Continuities

S - Specificky vyzkum na vysokych skolach

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Biomicrofluidics

ISSN

1932-1058

e-ISSN

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Volume of the periodical

7

Issue of the periodical within the volume

5

Country of publishing house

US - UNITED STATES

Number of pages

13

Pages from-to

"054103-1"-"054103-13"

UT code for WoS article

000326877600005

EID of the result in the Scopus database

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