A Solid Phase Vibrational Circular Dichroism Study of Polypeptide-Surfactant Interaction

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F15%3A43900287" target="_blank" >RIV/60461373:22340/15:43900287 - isvavai.cz</a>

Result on the web

<a href="http://onlinelibrary.wiley.com/doi/10.1002/chir.22534/abstract" target="_blank" >http://onlinelibrary.wiley.com/doi/10.1002/chir.22534/abstract</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/chir.22534" target="_blank" >10.1002/chir.22534</a>

Result language

angličtina

Original language name

A Solid Phase Vibrational Circular Dichroism Study of Polypeptide-Surfactant Interaction

Original language description

We studied the interaction of poly-l-lysine (PLL) and poly-l-arginine (PLAG) with sodium dodecyl sulfate (SDS) surfactant and the interaction of poly-l-glutamic acid (PLGA) and poly-l-aspartic acid (PLAA) with tetradecyltrimethylammonium bromide (TTAB) surfactant using vibrational circular dichroism (VCD) spectroscopy in the region of C-H stretching vibration and in the Amide I region both in solution and in mulls. A chirality transfer from polypeptides to achiral surfactants was observed in the C-H stretching region, where measurements in solution were impossible. This observation was enabled by a special sample treatment technique using lyophilization and the preparation of mulls. This technique demonstrated itself as an interesting and beneficial tool for VCD measurements. In addition, we observed that SDS changed the secondary structure of PLL to the -sheet and of PLAG to the -helix. TTAB disrupted the PLGA and PLAA structure. These results were obtained in the mull but were confir

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

BO - Biophysics

OECD FORD branch

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Project

<a href="/en/project/GAP208%2F11%2F0105" target="_blank" >GAP208/11/0105: Expanding the Optical Activity Method to the Realm of Biomolecules</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2015

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chirality

ISSN

0899-0042

e-ISSN

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Volume of the periodical

27

Issue of the periodical within the volume

12

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

965-972

UT code for WoS article

000364635600014

EID of the result in the Scopus database

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