Development of microfluidic chips for enzyme synthesis in ATPS

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F17%3A43914347" target="_blank" >RIV/60461373:22340/17:43914347 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Development of microfluidic chips for enzyme synthesis in ATPS
Original language description
Aqueous two-phase systems (ATPS) represent a good alternative for working with substances of biological origin. Aqueous two-phase systems are mainly used for extraction and purification of enzymes, proteins, and cells. ATPS can be used to control the transport of biological objects to a specific location of the microfluidic chip for further processing and analysis. In this work we will present shown the development of microfluidic chips for enzyme synthesis of antibiotic precursors in ATPS (enzymatic hydrolysis of Penicillin G to 6-APA). The microchips will be equipped by electrode chamber to apply DC electric field to a reaction mixture. Electric field should intensify mass tranfer of reaction products between the two phases. The main goal is to develop an efficient microreactor/microseparator for the production of valuable biological products.
Czech name
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Czech description
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Project
<a href="/en/project/GA17-09914S" target="_blank" >GA17-09914S: Reaction-transport fundamentals in integrated microfluidic bioreactors-separators operating with aqueous two-phase systems</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
PROCEEDINGS 44th International Conference of the Slovak Society of Chemical Engineering
ISBN
978-80-89597-58-1
ISSN
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e-ISSN
neuvedeno
Number of pages
5
Pages from-to
128-132
Publisher name
Slovak Society of Chemical Engineering
Place of publication
Bratislava
Event location
Demänovská dolina
Event date
May 22, 2017
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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