Electrochemical Detection of Sialic Acid Using Phenylboronic Acid-Modified Poly (Diaminobenzoic Acid) Electrodes
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F18%3A43915442" target="_blank" >RIV/60461373:22340/18:43915442 - isvavai.cz</a>
Alternative codes found
RIV/61388963:_____/18:00489957 RIV/00216208:11110/18:10376682
Result on the web
<a href="https://onlinelibrary.wiley.com/doi/abs/10.1002/elan.201700634" target="_blank" >https://onlinelibrary.wiley.com/doi/abs/10.1002/elan.201700634</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/elan.201700634" target="_blank" >10.1002/elan.201700634</a>
Alternative languages
Result language
angličtina
Original language name
Electrochemical Detection of Sialic Acid Using Phenylboronic Acid-Modified Poly (Diaminobenzoic Acid) Electrodes
Original language description
This study is focused on the electrochemical detection of sialic acid (SA) using electrochemical impedance spectroscopy (EIS) and potentiometric approaches with the polymeric film derived from 3,4-diaminobenzoic acid (3,4-DABA) and modified with 3-aminophenylboronic acid (3-APBA). The polymeric film derived from 3,4-DABA was prepared using cyclic voltammetry at 0.5 M H2SO4 on a platinum disc electrode from 0 to 1.20 V vs. Ag/AgCl and characterized by FTIR-Raman spectroscopy. It has been found that the polymerization process goes through the amino group and a free carboxyl group serves for the covalent binding of 3-APBA onto the polymeric backbone. Both the electrochemical approaches independently confirmed the recognition of SA by APBA-modified PDABA electrodes. In contrast to known electrochemical sensors in the literature, the APBA-modified PADABA sensor for SA gave a response in the range from 0.025 to 0.998 mM at neutral pH using the EIS method. The decrease in the EIS signal of ca 12 % was observed after two weeks of intensive use. Importantly, the selective APBA-modified polymeric electrode enabled the use of SA determination in artificial urine samples in a concentration range that is useful for diagnostic purposes, specifically 12–102 μg mL−1.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2018
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Electroanalysis
ISSN
1040-0397
e-ISSN
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Volume of the periodical
30
Issue of the periodical within the volume
4
Country of publishing house
DE - GERMANY
Number of pages
9
Pages from-to
672-680
UT code for WoS article
000429708900013
EID of the result in the Scopus database
2-s2.0-85037999868