Bioavailability and Stuctural Study of 20-Hydroxyecdysone Complexes with Cyclodextrins
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F19%3A43916327" target="_blank" >RIV/60461373:22340/19:43916327 - isvavai.cz</a>
Alternative codes found
RIV/60461373:22330/19:43916327
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0039128X18302113?via%3Dihub" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0039128X18302113?via%3Dihub</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.steroids.2018.11.007" target="_blank" >10.1016/j.steroids.2018.11.007</a>
Alternative languages
Result language
angličtina
Original language name
Bioavailability and Stuctural Study of 20-Hydroxyecdysone Complexes with Cyclodextrins
Original language description
20-Hydroxyecdysterone - (2beta,3beta,5beta,22R)-2,3,14,20,22,25-hexahydroxycholest-7-en-6-one was isolated in satisfactory yield using ethanol extraction from the aerial part of Silene wolgensis (Hornem.) Otth; sometimes Silene wolgensis (Willd.) Bess. ex Spreng. The complexation of the phytoecdysteroid with beta-cyclodextrin was studied by NMR spectroscopy. By studying the changes in chemical shifts of protons of substrates and receptors it was found that ecdysterone interacts with cyclodextrins to form supramolecular inclusion complexes of stoichiometric composition of 1:1 or 1:2. Ecdysterone-beta-cyclodextrin complexes exhibit 100 times higher solubility in water than the parent compound.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Steroids
ISSN
0039-128X
e-ISSN
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Volume of the periodical
147
Issue of the periodical within the volume
2019-Jul
Country of publishing house
US - UNITED STATES
Number of pages
5
Pages from-to
37-41
UT code for WoS article
000487004300007
EID of the result in the Scopus database
2-s2.0-85057559521