The preparation of mono- and multicomponent nanoparticle aggregates with layer-by-layer structure using emulsion templating method in microfluidics

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F22%3A43922737" target="_blank" >RIV/60461373:22340/22:43922737 - isvavai.cz</a>
Alternative codes found
RIV/68378271:_____/22:00546044
Result on the web
<a href="https://www.sciencedirect.com/science/article/pii/S0009250921006497" target="_blank" >https://www.sciencedirect.com/science/article/pii/S0009250921006497</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.ces.2021.117084" target="_blank" >10.1016/j.ces.2021.117084</a>

Result language
angličtina
Original language name
The preparation of mono- and multicomponent nanoparticle aggregates with layer-by-layer structure using emulsion templating method in microfluidics
Original language description
We report on the preparation of multicomponent hollow aggregates by an emulsion templating method adapted to microfluidic format. The method exploits partial miscibility of aqueous colloidal solutions as discrete phase and n-butanol as continuous phase. The aggregates consisted of an inner inorganic shell composed of iron oxide (IO) and gold nanoparticles (Au NPs) covered with polycaprolactone (PCL) NPs. The aggregates of smaller sizes were prepared compared to immiscible phases due to the diffusion-controlled shrinkage of aqueous droplets. The aggregate surface properties were controlled by using different mobilities and affinities of IO, Au, and PCL NPs to the water:n-butanol interface. The biocompatible surface layer enclosing an inorganic shell with a core space for possible cargo loading endowed these constructs with properties appreciated in medicinal applications. A computational fluid dynamics model enabled the prediction of the droplet size and formation frequency together with flow field properties at the point of droplet detachment.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
21002 - Nano-processes (applications on nano-scale); (biomaterials to be 2.9)

Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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