Long-Term Averaged Spectrum Descriptors of Dysarthria in Patients With Parkinson’s Disease Treated With Subthalamic Nucleus Deep Brain Stimulation
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F60461373%3A22340%2F22%3A43925514" target="_blank" >RIV/60461373:22340/22:43925514 - isvavai.cz</a>
Alternative codes found
RIV/68407700:21230/22:00362584 RIV/00216208:11110/22:10456563 RIV/00064165:_____/22:10456563
Result on the web
<a href="https://pubs.asha.org/doi/10.1044/2022_JSLHR-22-00308?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed" target="_blank" >https://pubs.asha.org/doi/10.1044/2022_JSLHR-22-00308?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1044/2022_JSLHR-22-00308" target="_blank" >10.1044/2022_JSLHR-22-00308</a>
Alternative languages
Result language
angličtina
Original language name
Long-Term Averaged Spectrum Descriptors of Dysarthria in Patients With Parkinson’s Disease Treated With Subthalamic Nucleus Deep Brain Stimulation
Original language description
Purpose: This study aimed to evaluate whether long-term averaged spectrum (LTAS) descriptors for reading and monologue are suitable to detect worsening of dysarthria in patients with Parkinson’s disease (PD) treated with subthalamic nucleus deep brain stimulation (STN-DBS) with potential effect of ON and OFF stimulation conditions and types of connected speech. Method: Four spectral moments based on LTAS were computed for monologue and reading passage collected from 23 individuals with PD treated with bilateral STN-DBS and 23 age-and gender-matched healthy controls. Speech performance of patients with PD was compared in ON and OFF STN-DBS conditions. Results: All LTAS spectral moments including mean, standard deviation, skew-ness, and kurtosis across both monologue and reading passage were able to significantly distinguish between patients with PD in both stimulation conditions and control speakers. The spectral mean was the only LTAS measure sensitive to capture better speech performance in STN-DBS ON, as compared to the STN-DBS OFF stimulation condition (p < .05). Standardized reading passage was more sensitive compared to monologue in detecting dysarthria severity via LTAS descriptors with an area under the curve of up to 0.92 obtained between PD and control groups. Conclusions: Our findings confirmed that LTAS is a suitable approach to objec-tively describe changes in speech impairment severity due to STN-DBS therapy in patients with PD. We envisage these results as an important step toward a continuum development of technological solutions for the automated assessment of stimulation-induced dysarthria. Supplemental Material: https://doi.org/10.23641/asha.21644798. © 2022 American Speech-Language-Hearing Association.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
20601 - Medical engineering
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2022
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Journal of Speech, Language, and Hearing Research
ISSN
1092-4388
e-ISSN
1558-9102
Volume of the periodical
65
Issue of the periodical within the volume
12
Country of publishing house
CZ - CZECH REPUBLIC
Number of pages
10
Pages from-to
4690-4699
UT code for WoS article
000931940600012
EID of the result in the Scopus database
2-s2.0-85143888537