Older age and type of surgery predict the early inflammatory response to hip trauma mediated by interleukin-6 (IL-6)
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61383082%3A_____%2F09%3A%230000057" target="_blank" >RIV/61383082:_____/09:#0000057 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11110/10:6937 RIV/00064165:_____/10:6937
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Older age and type of surgery predict the early inflammatory response to hip trauma mediated by interleukin-6 (IL-6)
Original language description
Hip trauma and surgery are associated with systemic inflammatory reaction. However, little evidence exists about the role of IL-6. In order to assess the inflammatory response, we evaluated white blood cell (WBC) count, C-reactive protein (CRP) and IL-6dynamics in sequential pre- and postsurgical samples collected from 125 elderly patients (mean age 78 +- 9 years) undergoing osteosynthesis (OS) for extracapsular hip fractures (n = 69), hemiarthroplasty (HA) or urgent total hip arthroplasty for intracapsular fractures (UA) (n = 35), and elective total hip arthroplasty for osteoarthrosis (OA) (n = 21). Both preoperative CRP and IL-6 levels were higher in patients with intracapsular fractures. IL-6 levels reached peak values immediately after the surgery, while CRP peak levels were reached 48 h after the surgery. The overall inflammatory reaction was more intense in HA patients compared to the other subgroups.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FJ - Surgery including transplantology
OECD FORD branch
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Result continuities
Project
<a href="/en/project/NR8830" target="_blank" >NR8830: Acute conditions in geriatric surgery</a><br>
Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Archives of Gerontology and Geriatries
ISSN
0167-4943
e-ISSN
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Volume of the periodical
2009
Issue of the periodical within the volume
15
Country of publishing house
US - UNITED STATES
Number of pages
4
Pages from-to
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UT code for WoS article
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EID of the result in the Scopus database
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