GC/MS determination of ibotenic acid and muscimol in the urine of patients intoxicated with Amanita pantherina
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61383082%3A_____%2F12%3A%230000102" target="_blank" >RIV/61383082:_____/12:#0000102 - isvavai.cz</a>
Alternative codes found
RIV/60162694:G44__/12:43875341
Result on the web
<a href="http://www.springerlink.com/content/x059rx1017602g1l/" target="_blank" >http://www.springerlink.com/content/x059rx1017602g1l/</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/s00414-011-0599-9" target="_blank" >10.1007/s00414-011-0599-9</a>
Alternative languages
Result language
angličtina
Original language name
GC/MS determination of ibotenic acid and muscimol in the urine of patients intoxicated with Amanita pantherina
Original language description
Authors of this article introduce an instrumental method of proving Amanita pantherina or A. muscaria poisoning. The article describes the isolation of ibotenic acid and muscimol from urine, the derivatization step and the determination of these compounds by gas chromatography/mass spectrometry. Isolation of these alkaloids from urine was performed on a strong cation exchanger (Dowex? 50W X8), and the elution and derivatization of the alkaloids were made in one step with ethyl chloroformate in aqueous solution of sodium hydroxide with the addition of ethanol and pyridine. Cycloserine was used as internal standard. By this method, concentrations of ibotenic acid and muscimol in the urine of four persons intoxicated with Amanita pantherina were determined. In this study mass spectra of derivatized ibotenic acid and muscimol are shown and validation of the method is described.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FP - Other medical fields
OECD FORD branch
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Result continuities
Project
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Continuities
V - Vyzkumna aktivita podporovana z jinych verejnych zdroju
Others
Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
International Journal of Legal Medicine
ISSN
0937-9827
e-ISSN
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Volume of the periodical
126
Issue of the periodical within the volume
4
Country of publishing house
US - UNITED STATES
Number of pages
6
Pages from-to
519-524
UT code for WoS article
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EID of the result in the Scopus database
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