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Cryopreservation of Platelets: Advances and Current Practice

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61383082%3A_____%2F18%3A00000439" target="_blank" >RIV/61383082:_____/18:00000439 - isvavai.cz</a>

  • Result on the web

    <a href="https://www.intechopen.com/books/cryopreservation-biotechnology-in-biomedical-and-biological-sciences" target="_blank" >https://www.intechopen.com/books/cryopreservation-biotechnology-in-biomedical-and-biological-sciences</a>

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Cryopreservation of Platelets: Advances and Current Practice

  • Original language description

    Conventional fresh platelets stored at 20–24°C have a short shelf life, at most 7 days. Their main disadvantage is logistics as it is more difficult. This limitation is especially problematic for emergency and intensive care departments for managing massive bleeding. The early and aggressive use of blood products for massive hemorrhage may correct coagulopathy, control bleeding, and improve outcomes. The timely availability of platelets at the shortest time after the injury is often problematic. Many hospitals cannot afford to have platelets permanently in stock because of its short shelf life. Cryopreservation and storage of frozen platelets may significantly prolong their shelf life. Thus, frozen platelets provide long-term accessibility in situations where fresh products are not available. The most widely used method for the platelets cryopreservation is freezing at 5–6% DMSO at −80°C. The production of cryopreserved platelets is not technologically demanding, they can be easily thawed and reconstituted. Frozen platelets are an alternative blood product for urgent orders in connection with heavy bleeding. They are cost-effective functional platelets product for the management of bleeding and should be considered for wider use in clinical practice, such as autologous platelets, rare or HLA/HPA compatible platelets and platelets for non-transfusion use.

  • Czech name

  • Czech description

Classification

  • Type

    C - Chapter in a specialist book

  • CEP classification

  • OECD FORD branch

    30205 - Hematology

Result continuities

  • Project

  • Continuities

    I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Others

  • Publication year

    2018

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Book/collection name

    Cryopreservation Biotechnology in Biomedical and Biological Sciences

  • ISBN

    978-1-78984-680-5

  • Number of pages of the result

    24

  • Pages from-to

    47-70

  • Number of pages of the book

    152

  • Publisher name

    IntechOpen

  • Place of publication

    London

  • UT code for WoS chapter