Emergency Supply Policy of Cryopreserved RBC and PLT: The Czech Republic Concept

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61383082%3A_____%2F20%3A00000793" target="_blank" >RIV/61383082:_____/20:00000793 - isvavai.cz</a>

Alternative codes found

RIV/68407700:21460/20:00349467

Result on the web

<a href="https://www.sciencedirect.com/science/article/abs/pii/S147305022030077X" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S147305022030077X</a>

DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Emergency Supply Policy of Cryopreserved RBC and PLT: The Czech Republic Concept

Original language description

Supply of blood for urgent substitution is a strategic logistical problem for the military medical services across the world. The limited shelf life of blood-derived bioproductsin the liquid state and the need for special transport and use conditions, apart from donor and donations availability are among the causes for concern. To solve these problems many national health-care authorities implemented the national emergency blood crisis policy, to get a large amount of blood at any time at any place in the case of disaster, terrorist attack or war. The civil therapeutic problems in immunohematolgy cases can also be solved by stocks of fresh and cryopreserved homologous or autologous blood for patients with rare RBCs antigens or HLA / HPA platelet refractoriness with no chance to use common blood. The short shelf life of fresh platelets limits their efficient inventory management and availability during a massive transfusion protocol. Building an inventory of frozen blood components can mitigate the risk of insufficient availability. Since the beginning of the century in the Czech Republic, used, like other countries, the use of of cryopreserved blood-derived bioproducts has become the current method used to overcome the shortages of a timely supply. The Military University Hospital, Prague, and its bank of cryopreserved blood have been operating under this policy since 2006. There is currently a stock of frozen RBCs for military reserve, for a national blood crisis and, also, a stock of rare RBC units. For crisis management there are also stored, frozen PLTs, which are used in the treatment of heavily bleeding polytrauma patients. Both the containment and research development mitigation policy programs are in place for civil / military emergency situations. Even pathogen reduced frozen PLTs and frozen RBCs were successfully investigated for clinical use if demands arose. Currently, it is possible to meet operational demand while reducing the number of resupply transports and loss of products due to expiration. A lesson has been learned from the current containment, reseach and mitigation programs of efficient blood supply management with cryopreserved blood and blood derived bioproducts.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30205 - Hematology

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2020

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

TRANSFUSION AND APHERESIS SCIENCE

ISSN

1473-0502

e-ISSN

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Volume of the periodical

59

Issue of the periodical within the volume

3

Country of publishing house

GB - UNITED KINGDOM

Number of pages

3

Pages from-to

1-3

UT code for WoS article

000538124200028

EID of the result in the Scopus database

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