Pituitary adenoma treatment plan quality comparison between linear accelerator volumetric modulated arc therapy and Leksell Gamma Knife (R) radiosurgery

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61383082%3A_____%2F21%3A00001130" target="_blank" >RIV/61383082:_____/21:00001130 - isvavai.cz</a>

Alternative codes found

RIV/00064203:_____/21:10429910 RIV/68407700:21340/21:00365187 RIV/68407700:21460/21:00365187

Result on the web

<a href="https://www.sciencedirect.com/science/article/abs/pii/S095839472100056X" target="_blank" >https://www.sciencedirect.com/science/article/abs/pii/S095839472100056X</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.meddos.2021.06.003" target="_blank" >10.1016/j.meddos.2021.06.003</a>

Result language

angličtina

Original language name

Pituitary adenoma treatment plan quality comparison between linear accelerator volumetric modulated arc therapy and Leksell Gamma Knife (R) radiosurgery

Original language description

The aim of this study was to compare radiosurgical treatment plan quality of a linear accelerator with Leksell Gamma Knife (LGK) for pituitary adenoma irradiation. Thirty pituitary adenoma patients were evaluated in this study. Treatment plans were prepared on LGK and stereotactic linear accelerator Varian TrueBeam STx. Volumetric Modulated Arc Therapy (VMAT) plans (21 plans with 2 coplanar arcs and 9 plans with 4 non-coplanar arcs) were calculated for linear accelerator. All the plans were evaluated in terms of conformity, selectivity, gradient index and organ at risk (OAR) sparing. VMAT produced dosimetrically comparable treatment plans to LGK regarding conformity and selectivity (New Conformity Index (NCI): 1.76 +/- 0.65 for 4 arc VMAT, 2.33 +/- 1,16 for 2 arc VMAT and 1.96 +/- 0.71 for LGK; Selectivity Index (SI): 0.63 +/- 0.16 for 4 arc VMAT, 0.51 +/- 0.16 for 2 arc VMAT and 0.58 +/- 0.17 for LGK). Gradient index (GI) was superior for LGK plans (GI: 2.74 +/- 0.20 for LGK and 5.28 +/- 2.29 for 4 arc VMAT). OAR sparing for optics, brainstem, and hypophysis was similar for both modalities while target volume coverage was maintained the same. Finally, treatment time resulted in favor of VMAT plans (in this study VMAT plans were almost 5 times faster than LGK treatment regarding beam on time). According to the results of this study stereotactic linear accelerator with VMAT treatment could be used as a reasonable alternative to LGK for pituitary adenoma radiosurgery but only if the same head fixation method accuracy and target volume delineation are maintained for both modalities. (c) 2021 American Association of Medical Dosimetrists. Published by Elsevier Inc. All rights reserved.

Czech name

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Czech description

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Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

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OECD FORD branch

30224 - Radiology, nuclear medicine and medical imaging

Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2021

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Medical Dosimetry

ISSN

0958-3947

e-ISSN

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Volume of the periodical

4

Issue of the periodical within the volume

440-448

Country of publishing house

US - UNITED STATES

Number of pages

1

Pages from-to

9

UT code for WoS article

000754202600025

EID of the result in the Scopus database

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