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Counterion binding to protamine polyion at a polarised liquid-liquid interface

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F07%3A00081284" target="_blank" >RIV/61388955:_____/07:00081284 - isvavai.cz</a>

  • Alternative codes found

    RIV/00216208:11120/07:00000389

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Counterion binding to protamine polyion at a polarised liquid-liquid interface

  • Original language description

    Conductometry, cyclic voltammetry and quasi-elastic light scattering (QELS) are used to study the counterion binding to protamine polyion in an aqueous solution of protamine sulphate and at the polarised interface between an aqueous solution of LiCl anda 1,2-dichloroethane solution of tetrabutylammonium tetraphenylborate (TBATPB), bis(triphenylphosphoranylidene)ammonium tetrakis(4-chlorophenyl)borate (BTPPATPBCl), or tetrapentylammonium tetrakis[3,5-bis(trifluoromethyl)phenyl]borate (TPeATFPB). It is shown that the conductivity of the aqueous solutions of protamine sulphate can be interpreted with the help of the Manning?Oosawa counterion condensation approach. Voltammetric measurements provide evidence of the formation of an ion-pair between protamine and the anion of the organic phase, which facilitates the transfer of protamine to the organic phase. The stability of the ion-pair decreases with the increasing anion size in the sequence TPB- > TPBCl- > TFPB-.

  • Czech name

    Vázání proti-iontu na protaminovým polyiontem na polarizovaném rozhraní kapalina-kapalina

  • Czech description

    Konduktometrie, cyklická voltametrie a metoda měření kvazi elastického rozptylu světla (QELS) byly použity ke studiu vázání proti-iontu na protamin ve vodném roztoku síranu protaminu na polarizovaném rozhraní mezi vodným roztokem LiCl a roztokem tetrabutyl amonium tetrafenyl borátu (TBATPB), bis(trifenylfosforanyliden) amonium tetrakis(4-chlorofenyl) borátu (TPeATPBCl) nebo tetrapentyl amonium tetrakis[3,5-bis(trifluoromethyl)fenyl] borátu (TPeATFPB) v 1,2-dichloroethanu.Bylo prokázáno, že vodivost vodných roztoků protaminu lze interpretovat s využitím Manning-Oosawova přístupu kondenzace proti-iontu. Voltametrická měření potvrdila tvorbu iontového páru mezi protaminem a aniontem v organické fázi, usnadňujícím přenos protaminu do organické faze. Stabilita iontového páru klesá se vzrůstající velikostí aniontu v pořadí >TPB->TPBCl->TFPB->TFPB-.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CG - Electrochemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/GA203%2F04%2F0424" target="_blank" >GA203/04/0424: Electrochemistry of biomedically important polyions at the interface of two immiscible electrolyte solutions with applications in drug analysis</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2007

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Journal of the Electroanalytical Chemistry and Journal of Electroanalytical Chemistry and Interfacial Electrochemistry

  • ISSN

    0022-0728

  • e-ISSN

  • Volume of the periodical

    603

  • Issue of the periodical within the volume

    2

  • Country of publishing house

    CH - SWITZERLAND

  • Number of pages

    8

  • Pages from-to

    235-242

  • UT code for WoS article

  • EID of the result in the Scopus database