A Multi Time-Scale Approach of the Lipid Bilayer Dynamics

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F12%3A00377702" target="_blank" >RIV/61388955:_____/12:00377702 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1016/B978-0-12-396533-2.00002-1" target="_blank" >http://dx.doi.org/10.1016/B978-0-12-396533-2.00002-1</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/B978-0-12-396533-2.00002-1" target="_blank" >10.1016/B978-0-12-396533-2.00002-1</a>

Result language
angličtina
Original language name
A Multi Time-Scale Approach of the Lipid Bilayer Dynamics
Original language description
The lipid bilayer is a supramolecular aggregate with complex dynamics. Independent and collective motions of lipid molecules span a wide range of timescales. In order to understand the lipid bilayer functioning, the correlation between various motions needs to be understood. Molecules with low molecular weight, when placed in the lipid bilayer, may alter membrane properties depending on their location. The effect of two membrane active molecules, ethanol and lidocaine, on the lipid bilayer was investigated in three different timescales by means of dedicated fluorescence techniques. The interfacial water dynamics was measured using ?solvent relaxation technique at picosecond timescale. The lateral lipid molecule mobility along the lipid bilayer surfacewas determined with fluorescence correlation spectroscopy at millisecond timescale, and collective lipid processes, such as spontaneous lipid pore formation, were monitored with fluorescence stopped-flow technique at the timescale of seco
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2012
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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