An investigation of suitable bag materials for the collection and storage of breath samples containing hydrogen cyanide

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F12%3A00384158" target="_blank" >RIV/61388955:_____/12:00384158 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1088/1752-7155/6/3/036004" target="_blank" >http://dx.doi.org/10.1088/1752-7155/6/3/036004</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1088/1752-7155/6/3/036004" target="_blank" >10.1088/1752-7155/6/3/036004</a>

Result language

angličtina

Original language name

An investigation of suitable bag materials for the collection and storage of breath samples containing hydrogen cyanide

Original language description

The SPACE study will assess exhaled breath hydrogen cyanide (HCN) concentrations as a marker of Pseudomonas aeruginosa (PA) infection in 240 children with cystic fibrosis (CF). It will use off-line selected ion flow tube mass spectrometry (SIFT-MS) analysis and so we needed to investigate which breath sampling bag material to use, the maximum storage time before analysis and the benefit of warming the bag samples. We studied 15 children with CF, 8 had chronic PA infection and 7 did not. Each exhaled directly into the instrument (on-line) and also into two 25 mu m thick Nalophan (25N), two 70 mu m Nalophan (70N) and two Tedlar (R) bags. Bags were stored at 20 or 37 degrees C. HCN concentrations were analysed at 1, 6, 24 and 48 h (off-line). Acetone andwater vapour concentrations were also measured in parallel. Correlation between on-line and off-line concentrations measured by SIFT-MS was better for all compounds and bag types at 37 degrees C. The median (IQR) on-line HCN concentration

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CF - Physical chemistry and theoretical chemistry

OECD FORD branch

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Project

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Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Breath Research

ISSN

1752-7155

e-ISSN

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Volume of the periodical

6

Issue of the periodical within the volume

3

Country of publishing house

GB - UNITED KINGDOM

Number of pages

7

Pages from-to

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UT code for WoS article

000308209100004

EID of the result in the Scopus database

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