Breath concentration of acetic acid vapour is elevated in patients with cystic fibrosis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F16%3A00462179" target="_blank" >RIV/61388955:_____/16:00462179 - isvavai.cz</a>

Alternative codes found

RIV/00064203:_____/16:10324780 RIV/00216208:11130/16:10324780

Result on the web

<a href="http://dx.doi.org/10.1088/1752-7155/10/2/021002" target="_blank" >http://dx.doi.org/10.1088/1752-7155/10/2/021002</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1088/1752-7155/10/2/021002" target="_blank" >10.1088/1752-7155/10/2/021002</a>

Result language

angličtina

Original language name

Breath concentration of acetic acid vapour is elevated in patients with cystic fibrosis

Original language description

A study has been carried out of the volatile organic compounds present in the exhaled breath of 58 cystic fibrosis (CF) patients. An important observation is that the acetic acid vapour concentration measured by selected ion flow tube mass spectrometry (SIFT-MS) is significantly elevated in the exhaled breath of CF patients, independent of the Pseudomonas aeruginosa (PA) infection status (PA-infected median 170 ppbv; PA-negative median 182 ppbv), compared to that of healthy controls (median 48 ppbv). The cause for this may be decreased pH of the mucus lining the CF airways. Thus, we speculate that non-invasive measurement of breath acetic acid concentration could serve as an indicator of the acidity of the CF airways mucosa. © 2016 IOP Publishing Ltd.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CF - Physical chemistry and theoretical chemistry

OECD FORD branch

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Project

<a href="/en/project/GA14-14534S" target="_blank" >GA14-14534S: Mass spectrometric quantification of volatile metabolites in breath for noninvasive diagnosis and monitoring of bacterial infection in cystic fibrosis</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2016

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Journal of Breath Research

ISSN

1752-7155

e-ISSN

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Volume of the periodical

10

Issue of the periodical within the volume

2

Country of publishing house

GB - UNITED KINGDOM

Number of pages

6

Pages from-to

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UT code for WoS article

000378091800002

EID of the result in the Scopus database

2-s2.0-84978670434