Electrochemical determination of 2-nitrofluorene and investigation of its interaction with DNA

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F16%3A00470879" target="_blank" >RIV/61388955:_____/16:00470879 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/16:10336639
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Electrochemical determination of 2-nitrofluorene and investigation of its interaction with DNA
Original language description
2-Nitrofluorene (2-NF) belongs to the group of nitrated polycyclic aromatic hydrocarbons. These compounds are categorized as environmental pollutants and they can manifest mutagenic and carcinogenic effects. A differential pulse voltammetric method at a glassy carbon electrode (GCE) was developed for sensitive determination of 2-NF. Under the optimum conditions found, a linear calibration dependence was obtained in the concentration range of 2 x 10(-7) - 1 x 10(-5) mol L-1, with the limit of quantification of 2 x 10 mol L-1. The practical applicability of this method was verified on the direct determination of 2-NF in a model sample of sand. Moreover, the mutual interaction between 2-NF and DNA was investigated using an electrochemical DNA biosensor (DNA-modified GCE). Cyclic voltammetry, electrochemical impedance spectroscopy, and square-wave voltammetry were employed in this study, confirming the formation of a 2-NF-DNA complex.n
Czech name
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Czech description
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Project
<a href="/en/project/GA15-02815S" target="_blank" >GA15-02815S: New recognition principles and approaches to electrochemical detection of tumor markers</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2016
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Proceedings of the 12th International students conference "Modern Analytical Chemistry"
ISBN
978-80-7444-044-1
ISSN
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e-ISSN
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Number of pages
6
Pages from-to
149-154
Publisher name
VŠCHT
Place of publication
Praha
Event location
Prague
Event date
Sep 22, 2016
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000391253800028

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