Determination of Three Tumor Biomarkers (Homovanillic Acid, Vanillylmandelic Acid, and 5‐Hydroxyindole‐3‐Acetic Acid) Using Flow Injection Analysis with Amperometric Detection

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F19%3A00498457" target="_blank" >RIV/61388955:_____/19:00498457 - isvavai.cz</a>

Alternative codes found

RIV/00216208:11310/19:10393969

Result on the web

<a href="http://hdl.handle.net/11104/0290822" target="_blank" >http://hdl.handle.net/11104/0290822</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1002/elan.201800540" target="_blank" >10.1002/elan.201800540</a>

Result language

angličtina

Original language name

Determination of Three Tumor Biomarkers (Homovanillic Acid, Vanillylmandelic Acid, and 5‐Hydroxyindole‐3‐Acetic Acid) Using Flow Injection Analysis with Amperometric Detection

Original language description

Flow injection analysis with amperometric detection (FIA‐AD) at screen‐printed carbon electrodes (SPCEs) in optimum medium of Britton‐Robinson buffer (0.04 mol ⋅ L−1, pH 2.0) was used for the determination of three tumor biomarkers (homovanillic acid (HVA), vanillylmandelic acid (VMA), and 5‐hydroxyindole‐3‐acetic acid (5‐HIAA)). Dependences of the peak current on the concentration of biomarkers were linear in the whole tested concentration range from 0.05 to 100 μmol ⋅ L−1, with limits of detection (LODs) of 0.065 μmol ⋅ L−1 for HVA, 0.053 μmol ⋅ L−1 for VMA, and 0.033 μmol ⋅ L−1 for 5‐HIAA (calculated from peak heights), and 0.024 μmol ⋅ L−1 for HVA, 0.020 μmol ⋅ L−1 for VMA, and 0.012 μmol ⋅ L−1 for 5‐HIAA (calculated from peak areas), respectively.n

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)

Project

<a href="/en/project/GA17-03868S" target="_blank" >GA17-03868S: New Methods of Electrochemical Monitoring of Biologically Active Organic Compounds in Environmental, Biological and Food Matrices</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2019

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Electroanalysis

ISSN

1040-0397

e-ISSN

—

Volume of the periodical

31

Issue of the periodical within the volume

2

Country of publishing house

DE - GERMANY

Number of pages

6

Pages from-to

303-308

UT code for WoS article

000459630500018

EID of the result in the Scopus database

2-s2.0-85055247557