Micellar electrokinetic chromatography as a powerful analytical tool for research on prebiotic chemistry
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F21%3A00543635" target="_blank" >RIV/61388955:_____/21:00543635 - isvavai.cz</a>
Alternative codes found
RIV/00216305:26620/21:PU141130
Result on the web
<a href="http://hdl.handle.net/11104/0320824" target="_blank" >http://hdl.handle.net/11104/0320824</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1016/j.microc.2021.106022" target="_blank" >10.1016/j.microc.2021.106022</a>
Alternative languages
Result language
angličtina
Original language name
Micellar electrokinetic chromatography as a powerful analytical tool for research on prebiotic chemistry
Original language description
Capillary electromigration techniques have proven their capabilities in detection of variety of analytes from inorganic ions and small organic molecules through bio(macro)molecules to large analytes such as cells or nano/ micro particles. Also broad range of potential applications includes food and environmental analysis, biomedical and pharmaceutical investigations or even diagnostics.nIn this work, it was demonstrated that capillary micellar electrokinetic chromatography is an excellent toolnextremely helpful in investigations focused on prebiotic synthesis of molecules essential for formation of life onnearly Earth – nucleobases. In particular, rapid separation of nucleobases (< 2 min) was achieved in 40 mM boratenbuffer separation electrolyte containing 60 mM sodium dodecyl sulfate as an additive. This approach enabledndetection of nucleobases formed in thermolysed formamide under conditions simulating the environmentnoccurring on early Earth. Moreover, polydopamine-based molecularly imprinted polymers specific to thyminenand uracil improved detection of these low abundant products.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10403 - Physical chemistry
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Microchemical Journal
ISSN
0026-265X
e-ISSN
1095-9149
Volume of the periodical
167
Issue of the periodical within the volume
AUG 2021
Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
106022
UT code for WoS article
000662640500005
EID of the result in the Scopus database
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