Combination of molecularly imprinted polymers and capillary electrophoresis for analysis of nucleobases

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F62156489%3A43210%2F19%3A43917121" target="_blank" >RIV/62156489:43210/19:43917121 - isvavai.cz</a>
Result on the web
<a href="https://mnet.mendelu.cz/mendelnet2019/mnet_2019_full.pdf" target="_blank" >https://mnet.mendelu.cz/mendelnet2019/mnet_2019_full.pdf</a>
DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Combination of molecularly imprinted polymers and capillary electrophoresis for analysis of nucleobases
Original language description
Determination of DNA damage products in various samples including urine, plasma or cells is an important process enabling the evaluation of the overall body condition. Therefore, a powerful sensitive and selective analytical technique is needed. Here, the combined use of molecularly imprinted polymeric biorecognition extraction and capillary electrophoretic separation with UV/Vis detection is demonstrated. The tagged analytes are nucleobases and their biologically important derivatives. Capillary micellar electrokinetic chromatography using sodium dodecyl sulphate enabled the baseline separation of cytosine and methylcytosine and imprinted polydopamine polymeric surface allowed for selective extraction of a selected nucleobase.
Czech name
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Czech description
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Publication year
2019
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
MendelNet 2019: Proceedings of International PhD Students Conference
ISBN
978-80-7509-688-3
ISSN
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e-ISSN
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Number of pages
4
Pages from-to
547-550
Publisher name
Mendelova univerzita v Brně
Place of publication
Brno
Event location
Brno
Event date
Nov 6, 2019
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
000576735500098

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