Voltammetry of Several Natural and Synthetic Opioids at a Polarized Ionic Liquid Membrane

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F21%3A00544237" target="_blank" >RIV/61388955:_____/21:00544237 - isvavai.cz</a>
Alternative codes found
RIV/61989592:15310/21:73609922
Result on the web
<a href="http://hdl.handle.net/11104/0321267" target="_blank" >http://hdl.handle.net/11104/0321267</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/celc.202100701" target="_blank" >10.1002/celc.202100701</a>

Result language
angličtina
Original language name
Voltammetry of Several Natural and Synthetic Opioids at a Polarized Ionic Liquid Membrane
Original language description
Cyclic voltammetry is used to examine the transfer of the protonated forms of several natural and synthetic opioids including fentanyl and its analogs, morphine, heroin and codeine, across the polarized interface between an aqueous electrolyte solution and an ionic liquid (IL) membrane. Besides demonstrating the possibility of an amperometric detection and determination, the voltammetric measurements provide the values of the ion partition coefficients and the standard Gibbs energy of ion transfer, along with the partition coefficients for the neutral opioids, which follow the sequence corresponding to the opioid analgesic potency. A correlation between the partition coefficients for the neutral and protonated opioids points to their common basis, which is the difference between the solvation energies of the partitioned species in water and IL phase. A comparison of the experimental and theoretical values of the standard Gibbs energy of ion transfer suggests that the solvophobic interactions play a key role.
Czech name
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Czech description
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Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)

Project
<a href="/en/project/GA20-07350S" target="_blank" >GA20-07350S: Electrochemical and analytical aspects of the transport of addictive and psychotropic drugs across the model biological barriers</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2021
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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