A New Hollow Fiber-Based Liquid-Phase Microextraction Method for the Determination of Antihypertensive Drug Lercanidipine in Biological Samples
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F24%3A00586282" target="_blank" >RIV/61388955:_____/24:00586282 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
A New Hollow Fiber-Based Liquid-Phase Microextraction Method for the Determination of Antihypertensive Drug Lercanidipine in Biological Samples
Original language description
A new hollow fiber-based liquid-phase microextraction (HF-LPME) method for the determination of antihypertensive drug lercandipine (LCN) in biological samples was developed. HF-LPME wasncombined with optimized square wave voltammetry (SWV) on a cathodically pre-treated screenprinted boron-doped diamond electrode (SP-BDDE). Optimum HF-LPME conditions were:nsupported liquid membrane (SLM) dodecane, 0.02 mol L-1 Britton-Robinson buffer (BRB, pH = 3) acceptor phase, BRB (pH = 7) donor phase, and time of extraction 30 min. Limits of quantification (LOQ) and detection (LOD) were 3.3 and 1.1 nmol L-1, respectively. The applicability of the developed method was verified on human urine, blood serum, and blood plasma with 20 and 100 nmol L-1 LCN addition.
Czech name
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Czech description
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Classification
Type
D - Article in proceedings
CEP classification
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OECD FORD branch
10405 - Electrochemistry (dry cells, batteries, fuel cells, corrosion metals, electrolysis)
Result continuities
Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2024
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Article name in the collection
Proceedings of the International Conference. 43rd Modern Electrochemical Methods
ISBN
978-80-908947-1-6
ISSN
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e-ISSN
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Number of pages
5
Pages from-to
116-120
Publisher name
Best servis
Place of publication
Ústí nad Labem
Event location
Jetřichovice
Event date
May 20, 2024
Type of event by nationality
WRD - Celosvětová akce
UT code for WoS article
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