Sonochemical synthesis of nanoparticles from bioactive compounds: advances, challenges, and future perspectives

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388955%3A_____%2F25%3A00639929" target="_blank" >RIV/61388955:_____/25:00639929 - isvavai.cz</a>

Result on the web

<a href="https://hdl.handle.net/11104/0370594" target="_blank" >https://hdl.handle.net/11104/0370594</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1016/j.ultsonch.2025.107559" target="_blank" >10.1016/j.ultsonch.2025.107559</a>

Result language

angličtina

Original language name

Sonochemical synthesis of nanoparticles from bioactive compounds: advances, challenges, and future perspectives

Original language description

Sonochemical synthesis, driven by acoustic cavitation, has emerged over the past two decades as a powerful and versatile method for producing nanoparticles of bioactive substances with enhanced physicochemical and biological properties. The extreme conditions generated by the collapse of cavitation bubbles-such as transient high temperatures and pressures-facilitate molecular fragmentation, nucleation, and controlled nanoparticle growth. These characteristics make sonochemistry particularly well suited for nanosizing pharmaceuticals, enzymes, and natural bioactive compounds. In addition to a wide range of experimental techniques, recent advances in molecular dynamics simulations have offered critical insights into the molecular-level mechanisms underlying sonochemical processes, revealing the roles of solvent interactions and interfacial dynamics in determining nanoparticle size and stability. This deeper understanding has enabled more precise tuning of synthesis parameters to achieve desired nanoparticle characteristics. Sonochemically synthesized nanoparticles have demonstrated significant potential in diverse biomedical fields, including targeted drug delivery, sonodynamic therapy, regenerative medicine, and antimicrobial coatings. This minireview consolidates two decades of research, highlighting key advancements in the sonochemical synthesis of nanoparticles of bioactive substances, with a focus on molecular-level insights, biomedical applications, future research directions, ongoing challenges, and future perspectives.

Czech name

—

Czech description

—

Type

J_imp - Article in a specialist periodical, which is included in the Web of Science database

CEP classification

—

OECD FORD branch

10403 - Physical chemistry

Project

<a href="/en/project/GF22-27317K" target="_blank" >GF22-27317K: Functionalization of biomaterial surfaces by bioactive substances: from fundamentals to application</a><br>

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2025

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Ultrasonics Sonochemistry

ISSN

1350-4177

e-ISSN

1873-2828

Volume of the periodical

121

Issue of the periodical within the volume

OCT 2025

Country of publishing house

NL - THE KINGDOM OF THE NETHERLANDS

Number of pages

18

Pages from-to

107559

UT code for WoS article

001584492900003

EID of the result in the Scopus database

2-s2.0-105016452710