Synthesis and cytostatic activity of 2,6-diamino-9-benzyl-9-deazapurine and related compounds.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F02%3A57020065" target="_blank" >RIV/61388963:_____/02:57020065 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Synthesis and cytostatic activity of 2,6-diamino-9-benzyl-9-deazapurine and related compounds.

Original language description

2,6-Diamino-9-benzyl-9-deazapurine and 9-benzyl-2,6-bis(benzylamino)-9-deazapurine were synthesized by reductive cyclization of the corresponding 6-cyanomethyl-5-nitropyrimidines. Both compounds exhibit cytostatic activity in human T-lymphoblastoid CCRF-CEM cells.

Czech name

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Czech description

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Type

D - Article in proceedings

CEP classification

CC - Organic chemistry

OECD FORD branch

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Project

<a href="/en/project/OC%20D13.20" target="_blank" >OC D13.20: New purine nucleoside analogues for therapeutic applications</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2002

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection

Chemistry of Nucleic Acid Components.

ISBN

80-86241-16-5

ISSN

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e-ISSN

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Number of pages

2

Pages from-to

38-39

Publisher name

UOCHB AV ČR

Place of publication

Praha

Event location

Špindlerův Mlýn [CZ]

Event date

Sep 3, 2002

Type of event by nationality

WRD - Celosvětová akce

UT code for WoS article

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