Cystatic activity of antiviral acyclic nucleoside phosphonates in rodent lymphocytes.
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F03%3A19033002" target="_blank" >RIV/61388963:_____/03:19033002 - isvavai.cz</a>
Alternative codes found
RIV/68378041:_____/03:19033002
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Cystatic activity of antiviral acyclic nucleoside phosphonates in rodent lymphocytes.
Original language description
The major mechanism of antiviral action of acyclic nucleoside phosphonates is inhibition of virus-induced DNA polymerases and of reverse transcriptases. They inhibit eukaryotic DNA polymerases, as well. Their suppressive effects on proliferation of mammalian lymphocytes differ greatly in dependence on the chemical structure. No tight correlation between the cytostatic and antiviral effects has been observed.
Czech name
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Czech description
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Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
FR - Pharmacology and apothecary chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/GA305%2F00%2F0048" target="_blank" >GA305/00/0048: Immune mechanisms of action of antiviral acyclic nucleoside phosphonates (ANP)</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2003
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Toxicology and Applied Pharmacology
ISSN
0041-008X
e-ISSN
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Volume of the periodical
192
Issue of the periodical within the volume
N/A
Country of publishing house
US - UNITED STATES
Number of pages
8
Pages from-to
246-253
UT code for WoS article
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EID of the result in the Scopus database
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