Synthesis of optically active N 6 -alkyl derivatives of (R)-3-(adenin-9-yl)-2-hydroxypropanoic acid and related compounds.

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F03%3A57030109" target="_blank" >RIV/61388963:_____/03:57030109 - isvavai.cz</a>

Result on the web

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DOI - Digital Object Identifier

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Result language

angličtina

Original language name

Synthesis of optically active N 6 -alkyl derivatives of (R)-3-(adenin-9-yl)-2-hydroxypropanoic acid and related compounds.

Original language description

Reaction of 6-chloropurine and other nucleobases with (R)-oxiranecarboxylate was studied. Ethyl (R)-3-(6-chloropurin-9-yl)-2-hydroxypropanoate was hydrolyzed to corresponding acid and then treated with various amines to give a series of N 6 -substituted(R)-3-(adenin-9-yl)2-hydroxypropanoic acids.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CC - Organic chemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2003

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Collection of Czechoslovak Chemical Communications

ISSN

0010-0765

e-ISSN

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Volume of the periodical

68

Issue of the periodical within the volume

5

Country of publishing house

CZ - CZECH REPUBLIC

Number of pages

20

Pages from-to

931-950

UT code for WoS article

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EID of the result in the Scopus database

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