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Reinstatement of serum pregnanolone isomers and progesterone during alcohol detoxification therapy in premenopausal women

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F05%3A00021461" target="_blank" >RIV/61388963:_____/05:00021461 - isvavai.cz</a>

  • Alternative codes found

    RIV/00023761:_____/05:27 RIV/00216208:11110/05:00009503 RIV/00064165:_____/05:00001235

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Reinstatement of serum pregnanolone isomers and progesterone during alcohol detoxification therapy in premenopausal women

  • Original language description

    Serum allopregnanolone (3[alpha]-hydroxy-5[alpha]-pregnan-20-one; P3[alpha]5[alpha]), pregnanolone (P3[alpha]5[beta]), asopregnanolone (P3[beta]5[alpha]), epipregnanolone (P3[beta]5[beta], progesterone, pregnanolone sulfate (PregS), pregnanolone, and estradiol were measured in 20women during therapy by gas chromatography-mass spectrometry or radioimmunoassay. In conclusion, the reinstatement of progesterone, P3[alpha]5[alpha], and P3[beta]5[beta] serum levels demonstrates the favorable effect of detoxification therapy on both reproductive functions and the psychosomatic stability of premenopausal women treated for alcohol addiction.

  • Czech name

    Návrat k původním hodnotám pregnanolonových isomerů a progesteronu v séru během alkoholové detoxikační léčby u žen před menopausou

  • Czech description

    Allopregnanolone (3alfa-hydroxy-5alfa-pregnan-20-on, P3alfa,5alfa), pregnanolon (P3alfa,5beta), isopregnanolone (P3beta,5alfa), epipregnanolon (P3beta,5beta), progesteron, pregnenolon sulfát (PregS), pregnanolon a estradiol byly meřeny v séru 20 žen během terapie metodami plynové chromatografie-hmotnostní spektrometrie a radioimunoanalýzy. Návrat k původním hladinám progesteronu, P3alfa,5alfa a P3beta,5beta v séru ukázal zásadní efekt alkoholové detoxikační léčby na reprodukční funkce a psychosomatickoustabilitu u žen před menopausou léčených z alkoholové závislosti.

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CC - Organic chemistry

  • OECD FORD branch

Result continuities

  • Project

    Result was created during the realization of more than one project. More information in the Projects tab.

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2005

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Alcoholism-Clinical and Experimental Research

  • ISSN

    0145-6008

  • e-ISSN

  • Volume of the periodical

    29

  • Issue of the periodical within the volume

    6

  • Country of publishing house

    US - UNITED STATES

  • Number of pages

    8

  • Pages from-to

    1010-1017

  • UT code for WoS article

  • EID of the result in the Scopus database