Inhibition of human telomerase by diphosphates of acyclic nucleoside phosphonates
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F05%3A00022641" target="_blank" >RIV/61388963:_____/05:00022641 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Alternative languages
Result language
angličtina
Original language name
Inhibition of human telomerase by diphosphates of acyclic nucleoside phosphonates
Original language description
Diphosphates of the antiviral acyclic nucleoside phosphonates (ANSp) were evaluated in telomeric repeat amplification protocol (TRAP) for their ability to inhibit the extension of telomeres by human telomerase from human leukemia HL-60 cells. Data show that the most effective compound studied was the guanine derivative PMEGpp.
Czech name
Inhibice lidské telomerasy difosfáty acyklických nukleosidfosfonátů
Czech description
Studium inhibice lidské telomerasy z buněk HL-60 metodou TRAP, difosfáty acyklických nukleosidfosfonátů ukázalo, že nejúčinnější je PMEGpp.
Classification
Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Result continuities
Project
<a href="/en/project/1M0508" target="_blank" >1M0508: New Antivirals and Antineoplastics</a><br>
Continuities
Z - Vyzkumny zamer (s odkazem do CEZ)
Others
Publication year
2005
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Biochemical Pharmacology
ISSN
0006-2952
e-ISSN
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Volume of the periodical
70
Issue of the periodical within the volume
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Country of publishing house
US - UNITED STATES
Number of pages
7
Pages from-to
894-900
UT code for WoS article
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EID of the result in the Scopus database
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