All

What are you looking for?

All
Projects
Results
Organizations

Quick search

  • Projects supported by TA ČR
  • Excellent projects
  • Projects with the highest public support
  • Current projects

Smart search

  • That is how I find a specific +word
  • That is how I leave the -word out of the results
  • “That is how I can find the whole phrase”

Nerve Agents Assay Using Cholinesterase Based Biosensor

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F09%3A00332920" target="_blank" >RIV/61388963:_____/09:00332920 - isvavai.cz</a>

  • Alternative codes found

    RIV/60162694:G44__/09:00002134 RIV/00216208:11160/09:00210053 RIV/44555601:13440/09:00004904

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    Nerve Agents Assay Using Cholinesterase Based Biosensor

  • Original language description

    Electrochemical biosensor based on electric eel acetylcholinesterase (AChE) (EC 3.1.1.7) was performed for assay of nerve agents ? tabun, sarin, soman, cyclosarin, and VX. The biosensor used AChE as biorecognition element. The presence of nerve agents was accompanied by a strong inhibition of AChE activity. Enzyme activity is easily measurable by electrochemical oxidation of thiocholine created from acetylthiocholine (ATChCl) by AChE-catalyzed hydrolysis. The tested nerve agents were successfully assayed. The best limits of detection were achieved for sarin (5.8810-10 M) and VX (8.5110-10 M) after one-minute assay. The biosensor was found long term stable at low as well as laboratory temperature.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CF - Physical chemistry and theoretical chemistry

  • OECD FORD branch

Result continuities

  • Project

    <a href="/en/project/OVUOFVZ200807" target="_blank" >OVUOFVZ200807: Biosensors for determination of nerve agents and yperites using recombinant proteins and nanotechnology</a><br>

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Electroanalysis

  • ISSN

    1040-0397

  • e-ISSN

  • Volume of the periodical

    21

  • Issue of the periodical within the volume

    10

  • Country of publishing house

    DE - GERMANY

  • Number of pages

    6

  • Pages from-to

  • UT code for WoS article

    000266537700009

  • EID of the result in the Scopus database