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New bradykinin B-2 receptor antagonists - influence of C-terminal segment modifications on their pharmacological properties

The result's identifiers

  • Result code in IS VaVaI

    <a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F09%3A00347364" target="_blank" >RIV/61388963:_____/09:00347364 - isvavai.cz</a>

  • Result on the web

  • DOI - Digital Object Identifier

Alternative languages

  • Result language

    angličtina

  • Original language name

    New bradykinin B-2 receptor antagonists - influence of C-terminal segment modifications on their pharmacological properties

  • Original language description

    Analogues of the bradykinin antagonist [D-Arg(0),Hyp(3),Thi(5,8),D-Phe(7)]BK having in position 7 or 8 L-pipecolic acid or L-beta(2)-isoproline or L-beta(3)-homoproline and free or acylated N-terminal amino group were synthesized and biologically evaluated (isolated rat uterus and rat blood pressure tests). The results thus support the hypothesis about the existence of different types of BK receptors in the rat uterus and blood vessels.

  • Czech name

  • Czech description

Classification

  • Type

    J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

  • CEP classification

    CC - Organic chemistry

  • OECD FORD branch

Result continuities

  • Project

  • Continuities

    Z - Vyzkumny zamer (s odkazem do CEZ)

Others

  • Publication year

    2009

  • Confidentiality

    S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Data specific for result type

  • Name of the periodical

    Acta Biochimica Polonica

  • ISSN

    0001-527X

  • e-ISSN

  • Volume of the periodical

    56

  • Issue of the periodical within the volume

    4

  • Country of publishing house

    PL - POLAND

  • Number of pages

    8

  • Pages from-to

  • UT code for WoS article

    000276702200008

  • EID of the result in the Scopus database