Single- and Double-Headed Chemical Probes for Detection of Active Cathepsin D in a Cancer Cell Proteome

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F10%3A00346346" target="_blank" >RIV/61388963:_____/10:00346346 - isvavai.cz</a>

Alternative codes found

RIV/68378050:_____/10:00346346 RIV/00216208:11310/10:10108913

Result on the web

—

DOI - Digital Object Identifier

—

Result language

angličtina

Original language name

Single- and Double-Headed Chemical Probes for Detection of Active Cathepsin D in a Cancer Cell Proteome

Original language description

We present the design of activity-based probes for cathepsins D that are effective in a complex proteome. The probes consist of a binding module with a statin-containing peptidic core, a warhead module bearing a photoreactive group, and a reporter tag. The fluorescent and biotin tags make the probes a powerful tool for a wide range of "in-gel" and "on-blot" proteomic applications.

Czech name

—

Czech description

—

Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

—

Project

<a href="/en/project/IAA400550705" target="_blank" >IAA400550705: Regulation of cathepsins in breast cancer therapy</a><br>

Continuities

P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2010

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Chembiochem

ISSN

1439-4227

e-ISSN

—

Volume of the periodical

11

Issue of the periodical within the volume

11

Country of publishing house

DE - GERMANY

Number of pages

4

Pages from-to

—

UT code for WoS article

000281383200012

EID of the result in the Scopus database

—