Alpha-cyclodextrins reversibly capped with disulfide bonds

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F10%3A00350020" target="_blank" >RIV/61388963:_____/10:00350020 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Alpha-cyclodextrins reversibly capped with disulfide bonds
Original language description
Per-O-methyl-6I, 6IV-disulfanyl-6I, 6IV-dideoxy-alpha-cyclodextrin undergoes air-oxidation at pH 9 to exclusively form monomeric species having an intramolecular disulfide linkage capping the C6I and C6IV positions. Molecular models show that the disulfide bridge effectively closes the primary rim of the the cyclodextrin cavity and can be cleaved by reduction with dithiothreitol. Thus, the macrocyclic system can interchange the open-ended and cup-like forms by application of external stimuli.
Czech name
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Czech description
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Type
J<sub>x</sub> - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)
CEP classification
CC - Organic chemistry
OECD FORD branch
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Project
<a href="/en/project/IAA400550810" target="_blank" >IAA400550810: Cyclodextrin dimers connected with disulfide bonds</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)<br>Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year
2010
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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