Nitrogen source and growth stage of Candida albicans influence expression level of vacuolar aspartic protease Apr1p and carboxypeptidase Cpy1p

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F12%3A00379073" target="_blank" >RIV/61388963:_____/12:00379073 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1139/W2012-030" target="_blank" >http://dx.doi.org/10.1139/W2012-030</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1139/W2012-030" target="_blank" >10.1139/W2012-030</a>

Result language

angličtina

Original language name

Nitrogen source and growth stage of Candida albicans influence expression level of vacuolar aspartic protease Apr1p and carboxypeptidase Cpy1p

Original language description

The genes APR1 and CPY1 of the pathogenic yeast Candida albicans encode vacuolar aspartic protease and serine carboxypeptidase, respectively. Transcription of both APR1 and CPY1 was upregulated in mid-exponential phase, together with increasing size of the vacuoles, when C. albicans was cultivated in a rich medium at 30 °C. However, simultaneous up-regulation of protein synthesis occurred only for Cpy1p. Analysis of APR1 and CPY1 expression under nitrogen limited conditions revealed, that the genes wereregulated on both the transcriptional and translational level and detectable amounts of Apr1p were synthesized only when C. albicans was grown in nitrogen limited media.

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CE - Biochemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

Z - Vyzkumny zamer (s odkazem do CEZ)

Publication year

2012

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Canadian Journal of Microbiology

ISSN

0008-4166

e-ISSN

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Volume of the periodical

58

Issue of the periodical within the volume

5

Country of publishing house

CA - CANADA

Number of pages

4

Pages from-to

678-681

UT code for WoS article

000303659500015

EID of the result in the Scopus database

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