Effective Charge Determination of Dendrigraft Poly-L-lysine by Capillary Isotachophoresis

Result code in IS VaVaI

<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F13%3A00392215" target="_blank" >RIV/61388963:_____/13:00392215 - isvavai.cz</a>

Result on the web

<a href="http://dx.doi.org/10.1021/ma302125f" target="_blank" >http://dx.doi.org/10.1021/ma302125f</a>

DOI - Digital Object Identifier

<a href="http://dx.doi.org/10.1021/ma302125f" target="_blank" >10.1021/ma302125f</a>

Result language

angličtina

Original language name

Effective Charge Determination of Dendrigraft Poly-L-lysine by Capillary Isotachophoresis

Original language description

In this work, capillary isotachophoresis (ITP) was used to determine the effective charge of the first five generations of dendrigraft poly-L-lysines. This approach, which is based on the linear dependence of ITP zone length of the solute on its concentration and effective charge, offers a simple and straightforward method for effective charge determination. The cationic ITP system employed in this work yields good linearity, repeatability and sharp zones. The value of effective charge number per one lysine residue obtained for long linear poly-L-lysine is in a good agreement with the Manning theoretical value (0.5). Results obtained for dendrigraft poly-L-lysines show a dramatic decrease in the effective charge number per lysine residue with increasing generation number, from 0.84 for short oligolysines (generation 1) down to 0.08 for the fifth generation. This decrease in effective charge is due to the proximity of charged groups in the dendrigraft structure of higher generation numb

Czech name

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Czech description

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Type

J_x - Unclassified - Peer-reviewed scientific article (Jimp, Jsc and Jost)

CEP classification

CC - Organic chemistry

OECD FORD branch

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Project

Result was created during the realization of more than one project. More information in the Projects tab.

Continuities

I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year

2013

Confidentiality

S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Name of the periodical

Macromolecules

ISSN

0024-9297

e-ISSN

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Volume of the periodical

46

Issue of the periodical within the volume

2

Country of publishing house

US - UNITED STATES

Number of pages

8

Pages from-to

533-540

UT code for WoS article

000314081800023

EID of the result in the Scopus database

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