Nanodiamonds as Intracellular Probes for Imaging in Biology and Medicine

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F14%3A00441403" target="_blank" >RIV/61388963:_____/14:00441403 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1007/978-94-017-8896-0_18" target="_blank" >http://dx.doi.org/10.1007/978-94-017-8896-0_18</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1007/978-94-017-8896-0_18" target="_blank" >10.1007/978-94-017-8896-0_18</a>

Result language
angličtina
Original language name
Nanodiamonds as Intracellular Probes for Imaging in Biology and Medicine
Original language description
In recent years, diamond nanoparticles have received a great deal of attention due to their unique photophysical and biological properties. Nanodiamonds (NDs) show low toxicity and are considered to be a highly biocompatible carbon nanomaterial useful ina wide range of applications. Thanks to their ability to accommodate nitrogen-vacancy (N-V) color centers, NDs are a prime example of non-photobleachable fluorescent labels and nanosensors. Here, we present a survey of ND applications in biology and medicine with an emphasis on bioimaging. We focus on distinguishing the properties of detonation NDs and high-pressure high-temperature (HPHT) NDs and describing their physicochemical properties, structure and possible modifications by small molecules and biomolecules. We summarize and critically evaluate in vitro and in vivo data on ND toxicity and biocompatibility, cellular internalization, localization and targeting by surface-attached ligands. We discuss current achievements in bioimagi
Czech name
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Czech description
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Project
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Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace

Publication year
2014
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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