Chiroptical spectroscopy as a sensitive tool for the conformational analysis of antimicrobial peptides

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F15%3A00449041" target="_blank" >RIV/61388963:_____/15:00449041 - isvavai.cz</a>
Result on the web
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DOI - Digital Object Identifier
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Result language
angličtina
Original language name
Chiroptical spectroscopy as a sensitive tool for the conformational analysis of antimicrobial peptides
Original language description
We tested the utilization of electronic and vibrational circular dichroism for the conformational study of antimicrobial peptides on two examples: melectin and antapin in different solutions of liposomes and micelles mimicking bacterial or eukaryotic membranes. The results show significant content of the alpha-helical conformation in an environment mimicking the bacterial membrane, while it was considerably low in the eukaryotic membrane-mimicking environment.
Czech name
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Czech description
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Project
<a href="/en/project/GAP208%2F11%2F0105" target="_blank" >GAP208/11/0105: Expanding the Optical Activity Method to the Realm of Biomolecules</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2015
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

Article name in the collection
Proceedings of the 11th International Students Conference "Modern Analytical Chemistry"
ISBN
978-80-7444-036-6
ISSN
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e-ISSN
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Number of pages
7
Pages from-to
67-73
Publisher name
Charles University in Prague, Faculty of Science
Place of publication
Prague
Event location
Prague
Event date
Sep 22, 2015
Type of event by nationality
EUR - Evropská akce
UT code for WoS article
000383853900012

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