Amino Acid Interaction (INTAA) web server
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F17%3A00477161" target="_blank" >RIV/61388963:_____/17:00477161 - isvavai.cz</a>
Alternative codes found
RIV/00216208:11310/17:10368209
Result on the web
<a href="https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/gkx352" target="_blank" >https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/gkx352</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1093/nar/gkx352" target="_blank" >10.1093/nar/gkx352</a>
Alternative languages
Result language
angličtina
Original language name
Amino Acid Interaction (INTAA) web server
Original language description
Large biomolecules-proteins and nucleic acids-are composed of building blocks which define their identity, properties and binding capabilities. In order to shed light on the energetic side of interactions of amino acids between themselves and with deoxyribonucleotides, we present the Amino Acid Interaction web server (http://bioinfo.uochb.cas.cz/INTAA/). INTAA offers the calculation of the residue Interaction Energy Matrix for any protein structure (deposited in Protein Data Bank or submitted by the user) and a comprehensive analysis of the interfaces in protein-DNA complexes. The Interaction Energy Matrix web application aims to identify key residues within protein structures which contribute significantly to the stability of the protein. The application provides an interactive user interface enhanced by 3D structure viewer for efficient visualization of pairwise and net interaction energies of individual amino acids, side chains and backbones. The protein-DNA interaction analysis part of the web server allows the user to view the relative abundance of various configurations of amino acid-deoxyribonucleotide pairs found at the protein-DNA interface and the interaction energies corresponding to these configurations calculated using a molecular mechanical force field. The effects of the sugar-phosphate moiety and of the dielectric properties of the solvent on the interaction energies can be studied for the various configurations.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10608 - Biochemistry and molecular biology
Result continuities
Project
<a href="/en/project/LM2015047" target="_blank" >LM2015047: Czech National Infrastructure for Biological Data</a><br>
Continuities
I - Institucionalni podpora na dlouhodoby koncepcni rozvoj vyzkumne organizace
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Nucleic Acids Research
ISSN
0305-1048
e-ISSN
—
Volume of the periodical
45
Issue of the periodical within the volume
W1
Country of publishing house
GB - UNITED KINGDOM
Number of pages
5
Pages from-to
"W388"-"W392"
UT code for WoS article
000404427000058
EID of the result in the Scopus database
2-s2.0-85023166913