Chiral analysis of alpha-diimine Ru(II) and Fe(II) complexes by capillary electrophoresis using sulfated cyclodextrins as stereoselectors
The result's identifiers
Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F17%3A00477878" target="_blank" >RIV/61388963:_____/17:00477878 - isvavai.cz</a>
Result on the web
<a href="http://dx.doi.org/10.1002/elps.201700077" target="_blank" >http://dx.doi.org/10.1002/elps.201700077</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1002/elps.201700077" target="_blank" >10.1002/elps.201700077</a>
Alternative languages
Result language
angličtina
Original language name
Chiral analysis of alpha-diimine Ru(II) and Fe(II) complexes by capillary electrophoresis using sulfated cyclodextrins as stereoselectors
Original language description
CE using randomly highly sulfated alpha-, beta-, and gamma-CDs (S-alpha-CD, S-beta-CD, S-gamma-CD), sulfobutylether-beta-CD (SBE-beta-CD), single isomer (6-O-sulfo) alpha-, beta-, and gamma-CDs, and their derivatives as stereoselectors was applied to chiral analysis of polypyridyl complexes of [Ru(bpy)(3)](2+), [Ru(phen)(3)](2+), and [Fe(phen)(3)](2+) (bpy = 2,2'-bipyridine, phen = 1,10 phenanthroline). The best separations of Delta- and Lambda-enantiomers of the these complexes with high resolution (up to R-1,R-2 = 7.0) and short analysis times (1020 min) were achieved in the BGE composed of 22 mM NaOH/35 mM H3PO4, pH 2.4, containing 1.56.0 mM S-alpha-CD or S-beta-CD, or SBE-beta-CD as chiral selectors. The developed method was applied to the assessment of enantiomeric purity of several samples of [Ru(bpy)(3)](2+) catalyst. CE experiments were performed in a homemade analyzer equipped with bare or hydroxypropylcellulose-coated fused-silica capillaries (total/effective length 40/29 cm, id/od 50/375 mu m) and an UV absorption detector operating at 206 nm. In addition to chiral analysis, apparent binding constants of the complexes of [Ru(bpy)(3)](2+), [Ru(phen)(3)](2+), and [Fe(phen)(3)](2+) enantiomers with five sulfated CDs (S-alpha-CD, S-beta-CD, S-gamma-CD, SBE-beta-CD, and 16Me-8S-gamma-CD) were determined from the dependence of their effective electrophoretic mobilities on the concentration of the CDs in the BGE by nonlinear regression analysis. Calculated apparent binding constants of these complexes were found to be in the (1.104.66) x 10(3) L/mol range. Moreover, it was shown that at selected concentrations of some S-CDs and suppressed or very low electroosmotic flow, the exceptional enantioseparations with infinite resolution could be achieved.
Czech name
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Czech description
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Classification
Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
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OECD FORD branch
10406 - Analytical chemistry
Result continuities
Project
Result was created during the realization of more than one project. More information in the Projects tab.
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)
Others
Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů
Data specific for result type
Name of the periodical
Electrophoresis
ISSN
0173-0835
e-ISSN
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Volume of the periodical
38
Issue of the periodical within the volume
15
Country of publishing house
DE - GERMANY
Number of pages
9
Pages from-to
1913-1921
UT code for WoS article
000406724200012
EID of the result in the Scopus database
2-s2.0-85019105617