5-(Hydroxymethyl) uracil and -cytosine as potential epigenetic marks enhancing or inhibiting transcription with bacterial RNA polymerase

Result code in IS VaVaI
<a href="https://www.isvavai.cz/riv?ss=detail&h=RIV%2F61388963%3A_____%2F17%3A00483893" target="_blank" >RIV/61388963:_____/17:00483893 - isvavai.cz</a>
Alternative codes found
RIV/61388971:_____/17:00483893 RIV/00216208:11310/17:10367080
Result on the web
<a href="http://dx.doi.org/10.1039/c7cc08053k" target="_blank" >http://dx.doi.org/10.1039/c7cc08053k</a>
DOI - Digital Object Identifier
<a href="http://dx.doi.org/10.1039/c7cc08053k" target="_blank" >10.1039/c7cc08053k</a>

Result language
angličtina
Original language name
5-(Hydroxymethyl) uracil and -cytosine as potential epigenetic marks enhancing or inhibiting transcription with bacterial RNA polymerase
Original language description
DNA templates containing 5-hydroxymethyluracil or 5-hydroxymethylcytosine were used in an in vitro transcription assay with RNA polymerase from Escherichia coli. A strong enhancement of transcription was observed from DNA containing the Pveg promoter whereas a decrease was observed from DNA containing the rrnB P1 promoter, suggesting that they may act as epigenetic marks.
Czech name
—
Czech description
—

Type
J<sub>imp</sub> - Article in a specialist periodical, which is included in the Web of Science database
CEP classification
—
OECD FORD branch
10608 - Biochemistry and molecular biology

Project
<a href="/en/project/GA17-03419S" target="_blank" >GA17-03419S: Artificial epigenetics: Development of a eukaryotic bioorthogonal transcription system for gene expression manipulation in the cell.</a><br>
Continuities
P - Projekt vyzkumu a vyvoje financovany z verejnych zdroju (s odkazem do CEP)

Publication year
2017
Confidentiality
S - Úplné a pravdivé údaje o projektu nepodléhají ochraně podle zvláštních právních předpisů

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